AXIN1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-1016	Proteintech Group Inc 165411AP150UL	150 μL

Description

Proteintech's AXIN1 antibody 16541-1-AP is a rabbit polyclonal antibody raised against the N-terminus of human AXIN1.

AXIN1 is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a disheveled and axin (DIX) domain and is thought to function as a negative regulator of the WNT signaling pathway that regulates embryonic axis formation. AXIN1 interacts with adenomatosis polyposis coli (APC), beta-catenin, glycogen synthase kinase 3 beta, forming a tetrameric complex resulting in the regulation of the stabilization of beta-catenin. Mutations in the AXIN1 gene have been associated various carcinomas, indicating that it also functions as a tumor suppressor.

Specifications

• Antigen: AXIN1
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O15169
• Gene ID (Entrez): 8312
• Immunogen: AXIN1 Fusion Protein Ag9858
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: AXIN1

• Concentration: 0.16 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: AXIN, axin 1, AXIN1, Axis inhibition protein 1, hAxin
• Gene Symbols: AXIN1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody