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Tocris Bioscience™ AY 9944 dihydrochloride
GSA_VAGREENER_CHOICE

Catalog No. 163910
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Catalog No. Quantity
16-391-0 10 mg
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Catalog No. 16-391-0 Supplier Tocris Bioscience™ Supplier No. 1639/10
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Description

Inhibitor of Hedgehog (Hh) signaling. Inhibits Δ7-dehydrocholesterol reductase

Inhibitor of hedgehog (Hh) signaling, possibly via several mechanisms. Inhibits Δ7-dehydrocholesterol reductase (IC50 = 13 nM), thus reduces cholesterol biosynthesis, and also inhibits cholesterol esterification. May also directly block the cellular response to Hh proteins. Teratogenic in vivo.

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Chemical Identifiers

CAS 366-93-8
Molecular Formula C22H30Cl4N2

Specifications

Quantity 10 mg
Formula Weight 464.3
Purity >99%
Molecular Weight (g/mol) 464.296
Chemical Name or Material AY 9944 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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