Learn More
Novus Biologicals™ AZD 5582 Dihydrochloride Inhibitor
Shop All Novus Biologicals Products

Description
Biological Activity: Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.
Storage: Store at 4°C.
Note: Inhibitors are guaranteed for 1 year from date of receipt.
Specifications
Specifications
Color | White |
Product Type | Inhibitor |
Target Proteins | AZD 5582 |
CAS | 548472-68-0 |
Molecular Formula | C30H30Cl2N4O4 |
Formula Weight | 1088.21g/mol |
Solubility | Soluble to 100mM in DMSO, 100mM in ethanol |
Content And Storage | Store at 4°C |
For Use With (Application) | Inhibits apoptosis |
Quantity | 10 mg |
For Research Use Only
Your input is important to us. Please complete this form to provide feedback related to the content on this product.