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  6. Novus Biologicals™ AZD 5582 Dihydrochloride Inhibitor

Novus Biologicals™ AZD 5582 Dihydrochloride Inhibitor
SDP

Catalog No. NB514110MG Shop All R&D Systems Products
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NB514110MG 10 mg
NB514150MG 50 mg
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Catalog No. NB514110MG Supplier Novus Biologicals™ Supplier No. NB514110MG

Description

Low molecular weight, organic compound that may help regulate biological process.

Biological Activity: Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.

Storage: Store at 4°C.

Note: Inhibitors are guaranteed for 1 year from date of receipt.

Specifications

Color White
Product Type Inhibitor
Target Proteins AZD 5582
CAS 548472-68-0
Molecular Formula C30H30Cl2N4O4
Formula Weight 1088.21g/mol
Solubility Soluble to 100mM in DMSO, 100mM in ethanol
Content And Storage Store at 4°C
For Use With (Application) Inhibits apoptosis
Quantity 10 mg

For Research Use Only

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