Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Protein Purification
  5. Protease Inhibitors and Phosphatase Inhibitors
  6. Novus Biologicals™ AZD 5582 Dihydrochloride Inhibitor

Novus Biologicals™ AZD 5582 Dihydrochloride Inhibitor
SDP

Catalog No. NB514150MG Shop All R&D Systems Products
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
NB514150MG 50 mg
NB514110MG 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. NB514150MG Supplier Novus Biologicals™ Supplier No. NB514150MG

Description

Low molecular weight, organic compound that may help regulate biological process.

Biological Activity: Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.

Storage: Store at 4°C.

Note: Inhibitors are guaranteed for 1 year from date of receipt.

Specifications

Color White
Product Type Inhibitor
Target Proteins AZD 5582
CAS 548472-68-0
Molecular Formula C30H30Cl2N4O4
Formula Weight 1088.21g/mol
Solubility Soluble to 100mM in DMSO, 100mM in ethanol
Content And Storage Store at 4°C
For Use With (Application) Inhibits apoptosis
Quantity 50 mg

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.