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Tocris Bioscience™ AZD 9272
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Catalog No. 561350
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56-135-0 50 mg
56-131-0 10 mg
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Catalog No. 56-135-0 Supplier Tocris Bioscience™ Supplier No. 5613/50
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Description

Potent and selective mGlu5 antagonist; brain penetrant

AZD 9272 is a potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.

Specifications

Chemical Name or Material 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
CAS 327056-26-8
Quantity 50 mg
Target Group I mGluR Antagonists
Molecular Formula C14H6F2N4O
Formula Weight 284.22
Purity >98%
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