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Tocris Bioscience™ AZD 9272
Potent and selective mGlu5 antagonist; brain penetrant
Supplier: Tocris Bioscience™ 5613/50
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Description
AZD 9272 is a potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.Specifications
3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile | |
50 mg | |
C14H6F2N4O | |
>98% |
327056-26-8 | |
Group I mGluR Antagonists | |
284.22 |
Safety and Handling
Recommended Storage : Store at Room Temperature
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