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Azelaic acid, tech. 80%

Catalog No. AAA1727136
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Catalog No. AAA1727136 Supplier Thermo Scientific Chemicals Supplier No. A1727136
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Description

CAS: 123-99-9 | C9H16O4 | 188.223 g/mol

It is applied in organic synthesis, lacquers, polyester adhesives, and urethane elastomers. Azelaic acid directly inhibits kallikrein 5 (KLK5), down regulating expression of KLK5, toll-like receptor 2 (TLR 2), and cathelicidin, and suppresses activity of serine proteases. In PUFA-treated fibroblasts, azelaic acid decreases generation of ROS and up regulates expression of antioxidative enzymes, inhibiting cell damage; agonist activity at PPAR? is thought to drive these effects. Azelaic acid also inhibits proliferation of melanocytes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Notes
Store away from strong oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 123-99-9
Molecular Formula C9H16O4
Molecular Weight (g/mol) 188.223
MDL Number MFCD00004432
InChI Key BDJRBEYXGGNYIS-UHFFFAOYSA-N
Synonym azelaic acid, finacea, anchoic acid, azelex, lepargylic acid, skinoren, 1,7-heptanedicarboxylic acid, heptanedicarboxylic acid, 1,9-nonanedioic acid, emerox 1110
PubChem CID 2266
ChEBI CHEBI:48131
IUPAC Name nonanedioic acid
SMILES C(CCCC(=O)O)CCCC(=O)O

Specifications

Melting Point ∼102°C
Boiling Point 286°C (100mmHg)
Beilstein 1101094
Merck Index 14,905
Solubility Information Soluble in water at 20°C 2.4g/L. Soluble in ethanol (5%),DMSO,methanol (70mg/ml),and alcohol.
Formula Weight 188.22
Percent Purity 80%
Grade Technical
Density 1.225
Quantity 500 g
Flash Point 215°C (419°F)
Chemical Name or Material Azelaic acid
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Safety and Handling

EINECSNumber 204-669-1
RTECSNumber CM1980000
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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