AZIN1 Monoclonal Antibody (OTI1G8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810899

Catalog No. 50-168-3698

Description

Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

Specifications

• Antigen: AZIN1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O14977
• Gene Symbols: AZIN1
• Immunogen: Human recombit protein fragment corresponding to amino acids 260-448 of human AZIN1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1G8
• Conjugate: Unconjugated
• Gene: AZIN1
• Gene Alias: AZI, AZI1, AZIA1, OAZI, OAZIN, ODC1L
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51582
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid