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AZIN1 Monoclonal Antibody (OTI3C3), TrueMAB™, OriGene
SDP

Catalog No. p-200015404
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100 μL
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50-168-3705 100 μL
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Catalog No. 50-168-3705 Supplier OriGene Supplier No. TA810907
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Mouse Monoclonal Antibody

Antizyme inhibitor (AZIN1) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

Specifications

Antigen AZIN1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3C3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene AZIN1
Gene Accession No. O14977
Gene Alias AZI, AZI1, AZIA1, OAZI, OAZIN, ODC1L
Gene Symbols AZIN1
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 260-448 of human AZIN1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51582
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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