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Invitrogen™ B-Myb Polyclonal Antibody
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Catalog No. PIPA579713
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100 μg
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PIPA579713 100 μg
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Catalog No. PIPA579713 Supplier Invitrogen™ Supplier No. PA579713
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Raji whole cell. IHC: human tonsil tissue, mouse liver tissue, rat liver tissue.

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen B-Myb
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Mybl2
Gene Accession No. P10244, P48972
Gene Alias B Myb; Bmyb; B-Myb; HGNC:7548; MGC15600; MYB proto-oncogene like 2; Mybl2; myb-like protein 2; Myb-related protein B; myeloblastosis oncogene-like 2; v-myb avian myeloblastosis viral oncogene homolog-like 2; v-myb myeloblastosis viral oncogene homolog (avian)-like 2; v-myb myeloblastosis viral oncogene homolog-like 2
Gene Symbols Mybl2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human B MyB (1-17aa MSRRTRCEDLDELHYQD).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17865, 296344, 4605
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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