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Tocris Bioscience™ B02
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Catalog No. p-7139265
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Catalog No. Quantity
63-925 5 mg
63-922-5 25 mg
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Catalog No. 63-925 Supplier Tocris Bioscience™ Supplier No. 6392/5
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Description

RAD51 recombinase inhibitor

B02 is a RAD51 recombinase inhibitor, exhibiting selectivity for human RAD51 over the E.coli homologue RecA (IC50 values are 27.4 μM and >250 μM, respectively). Inhibits homologous recombination and increases cellular sensitivity to DNA damage in vitro. Enhances the therapeutic effect of cisplatin (Cat. No. 2251) on tumor cells in vivo.

Specifications

CAS 1290541-46-6
Synonym 3-(Phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone
Quantity 5 mg
Molecular Formula C22H17N3O
Formula Weight 339.4
Purity 98%
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