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Invitrogen™ BACE2 Chimeric Recombinant Mouse Monoclonal Antibody (1/ 9)
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Catalog No. PIMA547981
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200 μg
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Catalog No. Quantity
PIMA547981 200 μg
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Catalog No. PIMA547981 Supplier Invitrogen™ Supplier No. MA547981
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Description

Mouse Recombinant Monoclonal Antibody

BACE2 Chimeric Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC

BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BACE2 Chimeric
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 1/ 9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene BACE2
Gene Accession No. Q9Y5Z0
Gene Alias 1110059C24Rik; 56 kDa aspartic-like protease; AEPLC; AI850424; ALP56; ARP1; asp 1; ASP1; ASP21; Aspartic-like protease 56 kDa; Aspartyl protease 1; Bace2; BAE2; be; beta secretase 2; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; memapsin-1; Membrane-associated aspartic protease 1; theta-secretase; transmembrane aspartic proteinase Asp1; UNQ418/PRO852
Gene Symbols BACE2
Host Species Mouse
Immunogen Human BACE2 244-333.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25825
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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