Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ BacMam LRRK2 Reagent
Click to view available options
Quantity:
15 mL
Description
BacMam LRRK2 Wild Type Reagent is a modified insect cell virus (baculovirus) that enables easy, efficient, and titratable overexpression of full-length wild-type LRRK2 in your choice of cellular background, including primary neurons and neuroblastoma cell lines.
BacMam LRRK2 Wild Type Reagent Lets You:
Easily overexpress full-length LRRK2 in most cellular backgrounds
Conduct the LRRK2 cellular assays you need
Understand the effects of therapeutically relevant LRRK2 mutations
Examine LRRK2 Mutations with BacMam Reagents
Use therapeutic mutant reagents G2019S (Cat. no. A13389) and D1994A (Cat. no. A13390) along with the wild-type LRRK2 reagent to enable your research into LRRK2 mutations, including exploration of differences in cellular response to stimulus among different mutations.
Expand Your Battery of Cellular Assays for LRRK2
Once full length LRRK2 has been introduced into your cellular background, the transduced cells allow you the flexibility to conduct many types of LRRK2 experiments, including studies of regulation of physiologically functional pathways (including signaling pathways leading to function), and identification of potential physiological substrates for LRRK2.
Overexpress Full-Length LRRK2 in Most Mammalian Cell Backgrounds
BacMam technology utilizes a modified baculovirus to deliver and express genes in mammalian cells with minimal effort and toxicity. It enables efficient, titratable LRRK2 protein expression in various mammalian cellular backgrounds, including cell lines that may not be compatible with traditional transfection methods, such as primary neurons and neuroblastoma cell lines.
For research use only. Not intended for any human or animal therapeutic or diagnostic use.
Related Links:
LRRK2 tools for advancing Parkinson's disease research
Kinase protein portfolio
LanthaScreen™ Eu Kinase Binding Assay
LanthaScreen™ Activity Assay
Learn More About BacMam Technology
BacMam LRRK2 Wild Type Reagent Lets You:
Examine LRRK2 Mutations with BacMam Reagents
Use therapeutic mutant reagents G2019S (Cat. no. A13389) and D1994A (Cat. no. A13390) along with the wild-type LRRK2 reagent to enable your research into LRRK2 mutations, including exploration of differences in cellular response to stimulus among different mutations.
Expand Your Battery of Cellular Assays for LRRK2
Once full length LRRK2 has been introduced into your cellular background, the transduced cells allow you the flexibility to conduct many types of LRRK2 experiments, including studies of regulation of physiologically functional pathways (including signaling pathways leading to function), and identification of potential physiological substrates for LRRK2.
Overexpress Full-Length LRRK2 in Most Mammalian Cell Backgrounds
BacMam technology utilizes a modified baculovirus to deliver and express genes in mammalian cells with minimal effort and toxicity. It enables efficient, titratable LRRK2 protein expression in various mammalian cellular backgrounds, including cell lines that may not be compatible with traditional transfection methods, such as primary neurons and neuroblastoma cell lines.
For research use only. Not intended for any human or animal therapeutic or diagnostic use.
Related Links:
Specifications
Specifications
| Formulation | Recombinant baculovirus particles suspended in Gibco™ Sf-900™ III SFM media supplemented with 3% heat-inactivated fetal bovine serum (hiFBS) |
| Type | BacMam LRRK2 Reagent |
| Target | Kinases |
| Delivery Type | Baculovirus (BacMam System) |
| Quantity | 15 mL |
| Content And Storage | Recombinant baculovirus particles suspended in Gibco™ Sf-900™ III SFM media (Cat# 12658) supplemented with 3% heat-inactivated fetal bovine serum (hiFBS) (Cat# 10100). Store at 4°C, keep sterile, protect from light, DO NOT freeze, aliquot upon arrival. |
| Gene Symbol | LRRK2 |
| Human Protein Class | Kinases |
| Shipping Condition | Wet Ice |
| For Use With (Application) | Overexpression of full-length wild-type LRRK2 |
For Research Use Only. Not for use in diagnostic procedures.
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction