Invitrogen™ BAF53A/BAF53B Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518272

Catalog No. PIPA518272

Description

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain.

Specifications

• Antigen: BAF53A/BAF53B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTL6B
• Gene Alias: 2810432C06Rik; 53 kDa BRG1-associated factor A; 53 kDa BRG1-associated factor B; actin like 6A; actin like 6B; actin-like 6; actin-like 6A; actin-like 6B; actin-like protein 6A; Actin-like protein 6B; actin-related protein 4; actin-related protein Baf53a; Actin-related protein Baf53b; Actl6; Actl6a; ACTL6B; AI851094; Arp4; ArpNa; arpNalpha; ArpN-alpha; ArpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; Baf53a; BAF53B; BRG1/brm-associated factor 53A; BRG1-associated factor 53A; BRG1-associated factor 53B; C79802; hArpN alpha; hArpN beta; INO80 complex subunit K; INO80K; MGC5382 Arp4
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 288563, 361925, 51412, 56456, 83766, 86
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O94805, O96019, P86173, Q99MR0, Q9Z2N8
• Gene Symbols: ACTL6A, ACTL6B
• Immunogen: Synthetic peptide sequence (YEEGGKQCVERKCP) corresponding to the C-terminus amino acids of ACTL6A / ACTL6B.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG