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Invitrogen™ BAG2 Monoclonal Antibody (8F11G2)
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Catalog No. PIMA549282
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100 μg
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Catalog No. Quantity
PIMA549282 100 μg
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Catalog No. PIMA549282 Supplier Invitrogen™ Supplier No. MA549282
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2. Positive Control - WB: human Jurkat whole cell, human Hela whole cell, human HepG2 whole cell, human K562 whole cell, mouse liver tissue. Flow: K562 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAG2
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone 8F11G2
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene BAG2
Gene Accession No. O95816, Q91YN9
Gene Alias 2610042A13Rik; BAG cochaperone 2; BAG family molecular chaperone regulator 2; BAG2; BAG-2; BAG-family molecular chaperone regulator-2; BC016230; BCL2 associated athanogene 2; Bcl-2-associated athanogene 2; Bcl2-associated athanogene 2; dJ417I1.2; dJ417I1.2 (BAG-family molecular chaperone regulator 2); KIAA0576; MGC149462; RP3-496N17.2
Gene Symbols BAG2
Host Species Mouse
Immunogen E.coli-derived human BAG2 recombinant protein (Position: M1-N211).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 213539, 9532
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG1
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