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Invitrogen™ BAG3 Polyclonal Antibody
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Catalog No. PIPA553818
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100 μL
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PIPA553818 100 μL
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Catalog No. PIPA553818 Supplier Invitrogen™ Supplier No. PA553818
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DSVDPEGRAD VRQARRDGVR KVQTILEKLE QKAIDVPGQV QVYELQPSNL EADQPLQAIM EMGAVAADKG KKNAGNAEDP HTETQQPEAT AAATSNPSSM TDTPGNPAAP Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 80%.

BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAG3
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene BAG3
Gene Accession No. O95817
Gene Alias AA407278; BAG family molecular chaperone regulator 3; BAG3; BAG-3; BCL2 associated athanogene 3; Bcl-2-associated athanogene 3; Bcl2-associated athanogene 3; BCL2-binding athanogene 3; bcl-2-binding protein Bis; Bcl-2-interacting death suppressor; BIS; CAIR-1; DKFZp434E0610; docking protein CAIR-1; MFM6; mg638; MGC104307; MNCb-2243
Gene Symbols BAG3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BAG3. Recombinant protein control fragment (Product #RP-92057).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9531
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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