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Invitrogen™ BAG4 Polyclonal Antibody
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Catalog No. 01675642
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100 μg
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Catalog No. Quantity
01-675-642 100 μg
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Catalog No. 01-675-642 Supplier Invitrogen™ Supplier No. PA141302
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Description

Rabbit Polyclonal Antibody

Suggested positive control: Hela whole cell extract, HeLa cell lysate.

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BAG4
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene BAG4
Gene Accession No. O95429
Gene Alias 2410112I15Rik; BAG cochaperone 4; BAG family molecular chaperone regulator 4; BAG4; BAG-4; BAG-family molecular chaperone regulator-4; BCL2 associated athanogene 4; Bcl-2-associated athanogene 4; BCL2-associated athanogene 4; silencer of death domains; SODD
Gene Symbols BAG4
Host Species Rabbit
Immunogen Peptide corresponding to amino acids 443-457 of human SODD protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9530
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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