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Banoxantrone dihydrochloride

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Quantity:
5 mg
25 mg
Description
Banoxantrone dihydrochloride is a bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4. Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM). Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat. No. 4091) in a mouse tumor model.
Specifications
Specifications
Chemical Name or Material | 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride |
CAS | 252979-56-9 |
Assay Percent Range | >98% |
Quantity | 5 mg |
Molecular Formula | C22H28N4O6.2HCl |
Formula Weight | Observed MW: 517.4 |
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