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Invitrogen™ BATF Recombinant Mouse Monoclonal Antibody (MBM7C7)

Catalog No. 740180M
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74-018-0M 100 μL
74-018-0MXS 20 μL
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Catalog No. 74-018-0M Supplier Invitrogen™ Supplier No. 740180M
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Mouse Recombinant Monoclonal Antibody

Recombinant mouse monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BATF
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone MBM7C7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2-7.4
Gene Batf
Gene Accession No. Q16520
Gene Alias activating transcription factor B; basic leucine zipper ATF-like transcription factor; basic leucine zipper transcription factor, ATF-like; basic leucine zipper transcription factor-like; basic leucine zipper transcriptional factor ATF-like; BATF; B-ATF; BATF1; B-cell activating transcription factor; B-cell-activating transcription factor; SFA2; SFA-2; SF-HT-activated gene 2 protein; si:ch211-153j24.4
Gene Symbols Batf
Host Species Mouse
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10538
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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