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BAX Mouse anti-Human, Mouse, Rat, Clone: 4G5E8, Proteintech
SDP

Mouse Monoclonal Antibody

$518.60

Specifications

Antigen BAX
Clone 4G5E8
Concentration 1.6 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-6364
SDP
Encompass_Preferred
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Proteintech Group Inc
602671IG150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3′ UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis. Overexpression of BAX functions to promote cell death. BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.
Specifications

Specifications

BAX
1.6 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Apoptosis regulator BAX, BAX
Bax
IgG2b
Protein A
Antibody
4G5E8
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Mouse
Human, Mouse, Rat
Q07812, Q07813, Q63690
12028, 24887, 581
BAX Fusion Protein Ag21068
Primary
-20°C
BAX
Videos
SDS
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Documents

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