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Tocris™ BAY 293

Catalog No. 68575
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68-575 5 mg
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Catalog No. 68-575 Supplier Tocris™ Supplier No. 6857/5
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Description

Potent KRas/SOS1 interaction inhibitor

BAY 293 is a potent KRas/son of sevenless 1 (SOS1) interaction inhibitor (IC50 = 21 nM); active R-enantiomer. Downregulates active RAS in tumor cells. Inhibits RAS-RAF-MEK-ERK pathway. Exhibits synergistic effects with KRASG12C inhibitor ARS-853.

Negative control also available.

Specifications

Chemical Name or Material (R)-6,7-Dimethoxy-2-methyl-N-[1-[4-[2-[(methylamino)methyl]phenyl]thiophene-2-yl]ethyl]quinazolin-4-amine
CAS 2244904-70-7
Quantity 5 mg
Molecular Formula C25H28N4O2S
Purity 98%
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