Invitrogen™ BCAS4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520907

Catalog No. PIPA520907

Description

A suggested positive control is NIH-3T3 cell lysate. PA5-20907 can be used with blocking peptide PEP-1021.

The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.

Specifications

• Antigen: BCAS4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCAS4
• Gene Alias: BCAS4; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 4; breast carcinoma amplified sequence 4/3 fusion protein; breast carcinoma-amplified sequence 4; CNOL; RP5-1071L10.2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55653
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q8TDM0
• Gene Symbols: BCAS4
• Immunogen: A 14 amino acid peptide near the amino terminus of human BCAS4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG