BCCIP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 160431AP
DescriptionThis gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|BCCIP, Protein TOK 1, TOK 1, TOK1|
|361666, 56647, 66165|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|BCCIP Fusion Protein Ag8934|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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