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BCCIP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 160431AP

Catalog No. 50-173-0670


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Description

Description

This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
Specifications

Specifications

BCCIP
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9CWI3, Q9P287
BCCIP, Protein TOK 1, TOK 1, TOK1
Rabbit
IgG
150 μL
-20°C
Primary
361666, 56647, 66165
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
BCCIP
Liquid
Bccip
BCCIP Fusion Protein Ag8934
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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