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Invitrogen™ Bcl-W Monoclonal Antibody (4G12E6)
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Catalog No. FERMA548388
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100 μg
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FERMA548388 100 μg
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Catalog No. FERMA548388 Supplier Invitrogen™ Supplier No. MA548388
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Mouse Monoclonal Antibody

Bcl-W Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow, ELISA

Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The 'rox' portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.
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Specifications

Antigen Bcl-W
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4G12E6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene BCL2L2
Gene Accession No. Q92843
Gene Alias Apoptosis regulator Bcl-W; AW048834; BCL2 like 2; BCL2L2; BCL2-L-2; BCL2-like 2; BCL2-like 2 protein; Bcl-2-like protein 2; Bcl2-like protein 2; BCLW; BCL-W; BCL-WEL; BCL-WS; c98; Gtrgal2; Gtrosa41; Kiaa0271; PPP1R51; protein phosphatase 1, regulatory subunit 51
Gene Symbols BCL2L2
Host Species Mouse
Immunogen Purified recombinant fragment of human BCL2L2 (AA: 6-118) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 599
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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