Invitrogen™ BCL6 Monoclonal Antibody (BL6.02 (PG-B6p))

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA511493

Catalog No. PIMA511493

Description

MA5-11493 targets BCL-6 in IHC (P) and Western blot applications and shows reactivity with Bovine, Human, Ovine, Porcine, Rabbit, Mouse and Rat samples. The MA5-11493 immunogen is recombinant protein corresponding to amino acids 3-484 of the human Bcl-6 protein.

Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.

Specifications

• Antigen: BCL6
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: tissue culture supernatant with 0.09% sodium azide
• Gene Accession No.: P41182, P41183
• Gene Symbols: BCL6
• Immunogen: Recombinant protein corresponding to amino acids 3-484 of the human Bcl-6 protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 100156549, 100353941, 101110557, 12053, 303836, 539020, 604
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: BL6.02 (PG-B6p)
• Conjugate: Unconjugated
• Gene: BCL6
• Gene Alias: B cell CLL/lymphoma 6; B cell leukemia/lymphoma 6; B-cell CLL/lymphoma 6; B-cell CLL/lymphoma 6 (zinc finger protein 51); B-cell leukemia/lymphoma 5; B-cell leukemia/lymphoma 6; B-cell lymphoma 5 protein; B-cell lymphoma 5 protein (BCL5); B-cell lymphoma 6 protein; B-cell lymphoma 6 protein homolog; B-cell lymphoma 6 protein transcript; BCL5; BCL-5; Bcl6; Bcl-6; BCL6 transcription repressor; BCL6A; cys his2 zinc finger transcription factor; cys-his2 zinc finger transcription factor; LAZ3; LAZ-3 protein; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); lymphoma-associated zinc finger gene on chromosome 3; protein LAZ-3; ZBTB27; zinc finger and BTB domain-containing protein 27; Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc finger protein 51; Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor BCL6S; ZNF51
• Host Species: Mouse
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Bovine, Sheep, Pig
• Product Type: Antibody
• Isotype: IgG1 κ

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov