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Invitrogen™ BCLAF1 Polyclonal Antibody
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01-675-087 100 μg
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Catalog No. 01-675-087 Supplier Invitrogen™ Supplier No. PA141680
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Description

Rabbit Polyclonal Antibody

PA1-41680 detects BCLAF1 in chimpanzee, canine, human and mouse samples. This antibody is expected to react with chicken and mosquito samples based on sequence homology. The amino acid sequence used as immunogen for this antibody is 87% homologous in Orangutan.

BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains.From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571.BCLAF1 is found to express mostly in skeletal muscles.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCLAF1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% gelatin and 0.05% sodium azide
Gene BCLAF1
Gene Accession No. Q8K019, Q9NYF8
Gene Alias 2610102K23Rik; 2700025J07Rik; 2810454G14Rik; 5730534O06Rik; Aa2-041; AI450190; AW556225; BCL2 associated transcription factor 1; bcl-2-associated transcription factor 1; BCL2-associated transcription factor 1; Bcl-2-associated transcription factor 1-like protein; BCLAF1; BCLAF1 and THRAP3 family member 1; bK211L9.1; BP-1; BTF; Btf-s; KIAA0164; mKIAA0164
Gene Symbols BCLAF1
Host Species Rabbit
Immunogen A portion of amino acids 700-750 of human BTF.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 483999, 72567, 9774
Target Species Human, Mouse, Canine, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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