BCLAF1 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5462	150 μL

Catalog No. 50-173-5462 Supplier Proteintech Group Inc Supplier No. 268091AP150UL

Description

Rabbit Polyclonal Antibody

BCLAF1 is an intracellular, death promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins. It shows homology to the basic leucine zipper (bzip) and MYB DNA binding domains.From recent research it can be concluded that in case of apoptotic cells this protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope. When over expressed this protein induces apoptosis and can be suppressed by co-expression of BCL2 proteins. Also known as BTF, it triggers a proapoptotic signal, potentially helpful to overcome the resistance to STI571.BCLAF1 is found to express mostly in skeletal muscles.

Specifications

• Antigen: BCLAF1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: BCLAF1
• Gene Accession No.: Q9NYF8
• Gene Alias: BCLAF1, bK211L9.1, BTF, KIAA0164
• Gene Symbols: BCLAF1
• Host Species: Rabbit
• Immunogen: BCLAF1 Fusion Protein Ag25210
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9774
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG