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Beclin 1 Mouse anti-Human, Mouse, Rat, Clone: 1C10C4, Proteintech
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Catalog No. 501737083 Shop All Proteintech Group Inc Products
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50-173-7083 150 μL
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Catalog No. 50-173-7083 Supplier Proteintech Group Inc Supplier No. 666651IG150UL
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Mouse Monoclonal Antibody

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.

Specifications

Antigen Beclin 1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1C10C4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene BECN1
Gene Accession No. O88597, Q14457, Q91XJ1
Gene Alias ATG6, Beclin 1, beclin 1, autophagy related, beclin1, BECN1, GT197, Protein GT197, VPS30
Gene Symbols Becn1
Host Species Mouse
Immunogen Beclin 1 Fusion Protein Ag1843
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114558, 56208, 8678
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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