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Invitrogen™ Beclin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA118287

Catalog No. 01-670-540


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Description

Description

PA1-18287 detects Beclin-1 from human samples. PA1-18287 has been successfully used in immunohistochemistry and immunofluorescence procedures. The PA1-18287 immunogen is a synthetic peptide corresponding to the C-terminal residues of human Beclin-1, conjugated to Blue Carrier Protein. The sequence is 100% conserved in mouse and rat. Reconstitute with 100 μL of distilled water.

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Beclin 1
Polyclonal
Unconjugated
BECN1
4921513J16Rik; 5430417M23Rik; APG6; Atg6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2 interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; beclin1; beclin-1; Beclin-1; beclin-1; Beclin-1-C 35 kDa; Beclin-1-C 37 kDa; becn1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; GT197; hypothetical protein MGC73097; myosin-like BCL2 interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e; VPS30; zgc:73097
Rabbit
100 μL
Primary
Human
Antibody
IgG
Immunohistochemistry (Frozen)
Conc. Not Determined
whole serum with no preservative
Q14457
BECN1
Synthetic peptide corresponding to the C-terminal residues of human Beclin-1.
RUO
8678
-20°C, Avoid Freeze/Thaw Cycles
Lyophilized
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