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BECN1 Monoclonal Antibody (OTI3F3), TrueMAB™, OriGene
SDP

Catalog No. 501673579
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30 μL
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50-167-3579 100 μL
50-254-1484 30 μL
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Catalog No. 50-167-3579 Supplier OriGene Supplier No. TA502527
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Description

Mouse Monoclonal Antibody

Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.

Specifications

Antigen BECN1
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI3F3
Concentration 0.78 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene BECN1
Gene Accession No. Q14457, Q91XJ1
Gene Alias ATG6, VPS30, beclin1
Gene Symbols BECN1
Host Species Mouse
Immunogen Full length human recombit protein of human BECN1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114558, 8678
Target Species Human, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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