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beta Actin Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI1, liquid, TrueMAB™
SDP

Catalog No. 501683761
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100 μL
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50-168-3761 100 μL
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Catalog No. 50-168-3761 Supplier OriGene Supplier No. TA811000
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Description

Mouse Monoclonal Antibody

Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.

Specifications

Antigen beta Actin
Applications Western Blot
Classification Monoclonal
Clone OTI1
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene ACTB
Gene Accession No. O18840, P60709, P60710, P60711
Gene Alias BRWS1, PS1TP5BP1
Gene Symbols ACTB
Host Species Mouse
Immunogen Synthetic peptide corresponding to the N terminal of human beta-actin conjugated to KLH.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11461, 403580, 60, 81822
Target Species Canine, Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG3
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