Invitrogen™ beta Amyloid (1-42) Polyclonal Antibody, Biotin

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 443449

Catalog No. 44-344-9

Description

This beta Amyloid (1-42) antibody (44-3449) is purified from rabbit serum by epitope-specific affinity chromatography. Any reactivity towards both full length Abeta 40 and Abeta 43 protein has been eliminated through a series of preabsorption steps. This antibody shows no significant cross-reactivity against Abeta 40 or Abeta 43.

Beta amyloid is a 40-43 amino acid peptide cleaved from amyloid precursor protein by a protease, gamma-secretase. Beta Amyloid (1-40) (Amyloid beta 40 or Abeta 40) together with beta Amyloid (1-42) (Amyloid beta 42 or Abeta 42) are two major C-terminal variants of the amyloid beta protein, constituting the majority of amyloid beta proteins. Both the Amyloid beta 40 and Amyloid beta 42 alloforms are major components of the extracellular plaques found in Alzheimer's disease brain tissue.

Specifications

• Antigen: beta Amyloid (1-42)
• Classification: Polyclonal
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Gene Accession No.: P05067
• Gene Symbols: APP
• Immunogen: 1-42 of Amyloid Beta.
• Quantity: 25 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Dot Blot, Functional Assay, Radioimmune Assays (RIA)
• Conjugate: Biotin
• Gene: APP
• Gene Alias: A beta 1 42; A ß 1 42; A4; AAA; AB42; Abeta; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; Amyloid beta 1 42; amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; Amyloid ß; Amyloid-beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; Aß 1 42; B APP42; BAPP42; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); beta-amyloid precursor protein; betaApp; Beta-APP40; BetaAPP42; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTFgamma; Cvap; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; P3(40); P3(42); peptidase nexin-II; PN2; PN-II; PreA4; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2; ß APP42; ßAPP42
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 351
• Content And Storage: -20°C
• Form: Liquid