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CPC Scientific H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH 1MG

Supplier: CPC Scientific AMYD003B
42-residue peptide believed to be the major subunit of the vascular and plaque filaments in individuals with Alzheimer's disease, elderly people and patients with Trisomy 21 (Down's Syndrome). Inactive control.SEQUENCE: H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OHONE-LETTER SEQUENCE: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIAMOLECULAR FORMULA: C203H311N55O60S1MOLECULAR WEIGHT: 4514.04STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [107761-42-2]SYNONYMS: Amyloid beta-Protein (1-42), Abeta42RESEARCH AREA: Alzheimer's DiseaseREFERENCES:J.Kang et al., Nature, 325, 733 (1987)D.Goldgaber et al., Science, 235, 877 (1987)J.Murrell et al., Science, 254, 97 (1991)Neurobiology of Aging, 13, No.5 (1992)G.Bitan et al., Proc. Natl. Acad. Sci. USA, 100, 330 (2003)A.Jan et al., Nat. Protoc., 5, 1186 (2010)W.B.Stine et al., Methods Mol. Biol. , 670
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