Invitrogen™ beta Lactamase Monoclonal Antibody (8A5.A10), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA546004

Catalog No. PIMA546004

Description

MA1-10712 detects beta Lactamase from E. coli samples. MA1-10712 has been successfully used in ELISA and Western blot applications. The MA1-10712 immunogen is 5-His-tagged TEM-1 beta-lactamase.

The beta lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta lactams are structurally related through the presence of a core beta lactam ring. Bacterial resistance to beta lactams continues to increase, primarily due to the production of beta lactamases. Beta lactamases catalyze the hydrolysis of the beta lactam bond, which destroys antibacterial activity. Bacteria that produce TEM type or SHV type beta lactamases have point mutations in structural genes that have extended the substrate specificity of these beta lactamases. As a result, many of the beta lactamase producing Gram negative pathogens have become multidrug resistant.

Specifications

• Antigen: beta Lactamase
• Classification: Monoclonal
• Concentration: 1.6 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 8A5.A10
• Conjugate: Unconjugated
• Gene Alias: blaCTX-M-14; FLJ14902; G24; lactamase beta; LACTB; mitochondrial 39S ribosomal protein L56; MRPL56; Serine beta-lactamase-like protein LACTB, mitochondrial; UNQ843/PRO1781
• Immunogen: 5'-His-tagged TEM-1 beta-lactamase.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov