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Bexarotene, 98%, Thermo Scientific Chemicals Catalog No.: AAJ63701MC
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Bexarotene, 98%, Thermo Scientific Chemicals

Catalog No. AAJ63701MC
100 mg
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Quantity:
100 mg
300 mg

Catalog No. AAJ63701MC

Supplier: Thermo Scientific Chemicals J63701MC

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Synthetic retinoid analog with specific affinity for the retinoid X receptor

Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.

Solubility
Soluble in DMSO and ethanol

Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 153559-49-0
Molecular Formula C24H28O2
Molecular Weight (g/mol) 348.49
MDL Number MFCD00932428
InChI Key NAVMQTYZDKMPEU-UHFFFAOYSA-N
Synonym bexarotene, targretin, targrexin, targretyn, targret, bexarotenum, bexarotene usan, bexaroteno, bexaroten, targretin-gel
PubChem CID 82146
ChEBI CHEBI:50859
IUPAC Name 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
SMILES CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C

Specifications

Melting Point 220°C to 225°C
Color White
Quantity 100 mg
Merck Index 14,1194
Solubility Information Soluble in DMSO and ethanol
Formula Weight 348.48
Percent Purity ≥99%
Physical Form Powder
Chemical Name or Material Bexarotene

Certificates

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberN20L020 Certificate TypeCertificate of Analysis Date02/24/2025 Catalog NumberJ63701MC,J63701EXH
Lot NumberY11K030 Certificate TypeCertificate of Analysis Date11/19/2024 Catalog NumberJ63701MC,J63701EXH
Lot NumberU27K045 Certificate TypeCertificate of Analysis Date10/09/2024 Catalog NumberJ63701MC,J63701EXH
Lot NumberY28J039 Certificate TypeCertificate of Analysis Date01/01/2024 Catalog NumberJ63701MC,J63701EXH
Lot NumberY28J040 Certificate TypeCertificate of Analysis Date01/01/2024 Catalog NumberJ63701MC,J63701EXH
Hazard Category H302-H315-H319-H335
Hazard Statement GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
RTECSNumber DH6834830
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only

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