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Tonbo Bioscience Antibodies Biotin Anti-Mouse CD19 (1D3) ..... Cat. No. 30-0193-U025 ..... Size 25 µg
Supplier: Tonbo Bioscience 300193U025
Antibodies Biotin Anti-Mouse CD19 (1D3) ..... Cat. No. 30-0193-U025 ..... Size 25 µgThe 1D3 antibody reacts with mouse CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 and CD81, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells. The 1D3 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.
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