Biphenyl-4-sulfonyl chloride, 97%

Description

CAS: 1623-93-4 | C12H9ClO2S | 252.71 g/mol

It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.

Solubility
Reacts with water.

Notes
Store at room temperature. Keep away from moisture, bases and oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 1623-93-4
• Molecular Formula: C12H9ClO2S
• Molecular Weight (g/mol): 252.71
• MDL Number: MFCD00078658
• InChI Key: ALBQXDHCMLLQMB-UHFFFAOYSA-N
• Synonym: 4-biphenylsulfonyl chloride, 1,1'-biphenyl-4-sulfonyl chloride, biphenyl-4-sulfonyl chloride, 1,1'-biphenyl-4-sulphonyl chloride, 4-biphenylsulfonylchloride, 1,1'-biphenyl-4-sulfonylchloride, biphenyl-4-sulphonyl chloride, 4-phenylbenzene-1-sulfonyl chloride, 1,1-biphenyl-4-sulfonylchloride, pubchem20990
• PubChem CID: 74192
• SMILES: ClS(=O)(=O)C1=CC=C(C=C1)C1=CC=CC=C1

• Melting Point: 112°C to 117°C
• Boiling Point: 200°C to 205°C (6 mmHg)
• Quantity: 25 g
• UN Number: UN3261
• Beilstein: 2694373
• Sensitivity: Moisture sensitive
• Solubility Information: Reacts with water.
• IUPAC Name: 4-phenylbenzenesulfonyl chloride
• Formula Weight: 252.72
• Percent Purity: 97%
• Chemical Name or Material: Biphenyl-4-sulfonyl chloride

Safety and Handling

Hazard Category	H314-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
EINECSNumber	216-609-1
TSCA	No
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only