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  6. Thermo Scientific Chemicals Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered

Thermo Scientific Chemicals Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered

Catalog No. AAJ67216XF
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Description

Blasticidin S hydrochloride, CAS # 3513-03-9, is an antibiotic isolated from Streptomyces griseochromogenes that inhibits peptide bond formation by ribosome. | CAS: 3513-03-9 | C17H27ClN8O5 | 458.90 g/mol

Blasticidin S hydrochloride, acts quickly by inhibiting peptide bond formation by the ribosome. The blasticidin S resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative. Blasticidin S is used for the prevention of contamination of cell cultures.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Blasticidin S hydrochloride is an antibiotic that works by inhibiting peptide bond formation by the ribosome

Application

• Blasticidin S hydrochloride is a nucleoside antibiotic that inhibits protein synthesis in prokaryotic and eukaryotic cells
• It inhibits peptide bond formation by the ribosome

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 3-9-3513
Molecular Formula C17H27ClN8O5
Molecular Weight (g/mol) 458.90
MDL Number MFCD02091640
InChI Key YQXYQOXRCNEATG-UHFFFAOYNA-N

Specifications

Type Blasticidin S Hydrochloride
Physical Form Liquid
Packaging Plastic Bottle
Quantity 1 mL
Solubility Information Soluble in water. Insoluble in organic solvents.
SMILES Cl.CN(CCC(N)CC(=O)NC1C=CC(OC1C(O)=O)N1C=CC(N)=NC1=O)C(N)=N
IUPAC Name 6-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-[3-amino-5-(N-methylcarbamimidamido)pentanamido]-3,6-dihydro-2H-pyran-2-carboxylic acid hydrochloride
PubChem CID 77062
Chemical Name or Material Blasticidin S hydrochloride

Safety and Handling

TSCA No
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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