Thermo Scientific Chemicals Blasticidin S hydrochloride, 10 mg/ml in HEPES buffer, sterile-filtered

Catalog No. AAJ67216XF

Supplier: Thermo Scientific Chemicals J67216XF

Description

Blasticidin S hydrochloride, CAS # 3513-03-9, is an antibiotic isolated from Streptomyces griseochromogenes that inhibits peptide bond formation by ribosome. | CAS: 3513-03-9 | C17H27ClN8O5 | 458.90 g/mol

Blasticidin S hydrochloride, acts quickly by inhibiting peptide bond formation by the ribosome. The blasticidin S resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative. Blasticidin S is used for the prevention of contamination of cell cultures.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Blasticidin S hydrochloride is an antibiotic that works by inhibiting peptide bond formation by the ribosome

Application

• Blasticidin S hydrochloride is a nucleoside antibiotic that inhibits protein synthesis in prokaryotic and eukaryotic cells
• It inhibits peptide bond formation by the ribosome

Specifications

Chemical Identifiers

• CAS: 3-9-3513
• Molecular Formula: C17H27ClN8O5
• Molecular Weight (g/mol): 458.90
• MDL Number: MFCD02091640
• InChI Key: YQXYQOXRCNEATG-UHFFFAOYNA-N

• Type: Blasticidin S Hydrochloride
• Physical Form: Liquid
• Packaging: Plastic Bottle
• Quantity: 1 mL
• Solubility Information: Soluble in water. Insoluble in organic solvents.
• SMILES: Cl.CN(CCC(N)CC(=O)NC1C=CC(OC1C(O)=O)N1C=CC(N)=NC1=O)C(N)=N
• IUPAC Name: 6-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-[3-amino-5-(N-methylcarbamimidamido)pentanamido]-3,6-dihydro-2H-pyran-2-carboxylic acid hydrochloride
• PubChem CID: 77062
• Chemical Name or Material: Blasticidin S hydrochloride

Safety and Handling

TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only