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Invitrogen™ Blood Group A Antigen Monoclonal Antibody (HE-195)
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Catalog No. PIMA544036
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100 μg
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PIMA544036 100 μg
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Catalog No. PIMA544036 Supplier Invitrogen™ Supplier No. MA544036
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Description

Mouse Monoclonal Antibody

This antibody recognizes human blood group A including weak variants A3, AX, A3B, AXB. The specifity of antibody HE-195 was confirmed by comparison of specifity and reactivity to standard reagent using >5000 samples of blood.

Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
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Specifications

Antigen Blood Group A Antigen
Applications Flow Cytometry
Classification Monoclonal
Clone HE-195
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 15 mM sodium azide; pH 8
Gene ABO
Gene Accession No. P16442
Gene Alias A transferase; A1-specific alpha 1-3-N-acetylgalactosaminyltransferase; A3GALNT; A3GALT1; ABO; ABO A3 transferase; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO weak transfer; B transferase; B(A) alpha-1,3-galactosyltransferase; Blood Group A1; Blood Group A2; Blood Group A3; fucosylglycoprotein; fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; glycosyltransferase A; glycosyltransferase B; GTB; histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group ABO system transferase; Histo-blood group B transferase; NAGAT; Transferase; transferase A
Gene Symbols ABO
Host Species Mouse
Immunogen Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
Purification Method Sequential Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 28
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM
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