Invitrogen™ Blood Group A Antigen Monoclonal Antibody (HE-195)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135443

Catalog No. 01-671-498

Description

Human blood group A antigen belongs to a group of carbohydrate determinants carried on both glycolipids and glycoproteins; it is detected on erythrocytes and certain epithelial cells. The antibody HE-195 recognizes human blood group A including weak variants A3 , AX , A3B, AXB. The specifity of antibody HE-195 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood. Agglutination test A1, A1B, A2B.

Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Specifications

• Antigen: Blood Group A Antigen
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Tissue culture supernatant with <0.1% sodium azide
• Gene Accession No.: P16442
• Gene Symbols: ABO
• Immunogen: Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A.
• Regulatory Status: RUO
• Gene ID (Entrez): 28
• Content And Storage: 4°C
• Form: Liquid

• Applications: Agglutination
• Clone: HE-195
• Conjugate: Unconjugated
• Gene: ABO
• Gene Alias: A transferase; A1-specific alpha 1-3-N-acetylgalactosaminyltransferase; A3GALNT; A3GALT1; ABO; ABO A3 transferase; ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase); ABO glycosyltransferase; ABO weak transfer; B transferase; B(A) alpha-1,3-galactosyltransferase; Blood Group A1; Blood Group A2; Blood Group A3; fucosylglycoprotein; fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase; glycosyltransferase A; glycosyltransferase B; GTB; histo-blood group A transferase; histo-blood group A2 transferase; histo-blood group ABO system transferase; Histo-blood group B transferase; NAGAT; Transferase; transferase A
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM