Invitrogen™ BMP-6 Monoclonal Antibody (74219)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523844

Catalog No. PIMA523844

Description

In Western blots, no cross-reactivity with recombinant human (rh) BMP-2, rhBMP-4, rhBMP-5, or rhBMP-7 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

BMP6 is a member of bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

Specifications

• Antigen: BMP-6
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P22004
• Gene Symbols: BMP6
• Immunogen: CHO-derived recombinant human BMP-6 Arg296-His428.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Neutralization, Western Blot
• Clone: 74219
• Conjugate: Unconjugated
• Gene: BMP6
• Gene Alias: BMP; BMP 6; BMP6; BMP-6; Bone morphogenetic protein; Bone morphogenetic protein 6; D13Wsu115e; vegetal related growth factor (TGFB-related); vegetal-related (TGFB related) cytokine; VG-1-R; VG-1-related protein; Vg1-related sequence; Vgr; Vgr1; VGR-1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 654
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized