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Invitrogen™ BMP-8B Polyclonal Antibody
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Catalog No. FEPA5144815
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100 μL
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FEPA5144815 100 μL
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Catalog No. FEPA5144815 Supplier Invitrogen™ Supplier No. PA5144815
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DLQTLRAGDE GWLVLDVTAA SDCWLLKRHK DLGL Antigen sequence identity: Mouse 85%; Rat 82%.

BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. BMP-8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
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Specifications

Antigen BMP-8B
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Bmp8b
Gene Accession No. P34820
Gene Alias BMP; BMP8; BMP-8; Bmp8b; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP2; OP-2; Op3; Osteogenic protein 2
Gene Symbols Bmp8b
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 183-216. Recombinant protein control fragment (Product #RP-110010).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 656
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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