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Invitrogen™ BMPR1A Polyclonal Antibody
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Catalog No. 386000
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Catalog No. Quantity
38-600-0 100 μg
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Catalog No. 38-600-0 Supplier Invitrogen™ Supplier No. 386000
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Description

Rabbit Polyclonal Antibody

BMPR1A Polyclonal Antibody for Western Blot, ICC/IF, IP

BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser/thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BMPR1A
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene BMPR1A
Gene Accession No. P36894, P36895, Q78EA7
Gene Alias 10q23del; 1110037I22Rik; activin A receptor, type II-like kinase 3; activin receptor-like kinase 3; ACVRLK3; ALK3; ALK-3; AU045487; BMP type-1A receptor; BMP-2/BMP-4 receptor; Bmpr; Bmpr1a; BMPR-1A; BMPRIA; BMPR-IA; Bone morphogenetic protein 4 receptor; bone morphogenetic protein receptor type 1A; bone morphogenetic protein receptor type IA; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type 1A; bone morphogenetic protein receptor, type IA; CD292; Serine/threonine-protein kinase receptor R5; SKR5
Gene Symbols BMPR1A
Host Species Rabbit
Immunogen Synthetic peptide derived from an internal region of the human BMPR-1A (bone morphogenetic protein receptor type 1A, Serine/threonine protein kinase receptor R5 (SKR5), activin receptor-like kinase-3 (ALK-3)), which differs from mouse and rat BMPR-1A by one nonconservative amino acid replacement.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12166, 657, 81507
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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