Borane-tetrahydrofuran complex, 1M soln. in THF, stab. with 5mmol NaBH₄, Thermo Scientific™

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Borane-tetrahydrofuran complex is an important reagent used in the reduction of certain functional groups viz. aldehyde, ketone, carboxylic acid, amide, oxime, imine and nitrile. It is also used as hydro borating agent. It acts as a borane source for oxazaborolidine catalyzed asymmetric reductions. It is utilized to reduce nylon surface amide groups to secondary amines.

Solubility
Miscible and reacts violently with water.

Notes
Air and moisture sensitive. Forms explosive peroxides in contact with air. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents and alcohols. On hydrolysis, it forms hydrogen and boric acid.

Specifications

Chemical Identifiers

• CAS: 14044-65-6
• Molecular Formula: C4H11BO
• Molecular Weight (g/mol): 85.94
• MDL Number: MFCD00012429
• InChI Key: RMCYTHFAWCWRFA-UHFFFAOYSA-N
• Synonym: borane-tetrahydrofuran complex, tetrahydrofuran borane, bh3.thf, borane tetrahydrofuran complex solution, borane-d3-thf complex solution, borane-tetrahydrofuran, unii-5ear4err1l, oxolane borane, boron; oxolane, borane thf
• PubChem CID: 11062302
• IUPAC Name: boron;oxolane
• SMILES: B.C1CCOC1

• Density: 0.878
• Flash Point: −21°C (−8°F)
• Linear Formula: BH_3/(CH2)4O
• Quantity: 100 mL
• UN Number: UN3148
• Beilstein: 3668402
• Sensitivity: Air and moisture sensitive
• Solubility Information: Miscible and reacts violently with water.
• Formula Weight: 85.94
• Concentration or Composition (by Analyte or Components): 1M soln. in THF
• Chemical Name or Material: Borane-tetrahydrofuran Complex, stabilized with 5mmol NaBH₄

Safety and Handling

Hazard Category	H225-H260-H302-H315-H318-H335-H336-H351
Hazard Statement	GHS H Statement H225-H260-H318-H351-H302-H335-H315 Highly flammable liquid and vapor. In contact with water releases flammable gases which may ignite spontaneously. Causes serious eye damage. Suspected of causing cancer. Harmful if swallowed. May cause respiratory irritation. Causes skin irritation.
Precautionary Statement	P201-P202-P210-P223-P231+P232-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P281-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P310-P330-P332+P313-P335+P334
DOTInformation	Transport Hazard Class: 4.3; Packing Group: I; Proper Shipping Name: WATER-REACTIVE LIQUID, N.O.S.
EINECSNumber	237-881-8
TSCA	Yes
Recommended Storage	Keep cold; Store under Argon

SDS