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Invitrogen™ BPDE Monoclonal Antibody (8E11)
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Catalog No. 01676389
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100 μg
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Catalog No. Quantity
01-676-389 100 μg
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Catalog No. 01-676-389 Supplier Invitrogen™ Supplier No. MA140270
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Description

Mouse Monoclonal Antibody

This antibody recognizes free BPDE and DNA adducts.

A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representative PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BPDE
Applications ELISA, Immunoprecipitation
Classification Monoclonal
Clone 8E11
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene Alias Benzo[a]pyrenediol-epoxide; BPDE
Host Species Mouse
Immunogen BPDE.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Chemical
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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