Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ BPDE Monoclonal Antibody (8E11)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA140270
Description
This antibody recognizes free BPDE and DNA adducts.
A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representative PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.
Specifications
BPDE | |
Monoclonal | |
0.1 mg/mL | |
PBS with 0.1% BSA and 0.02% sodium azide | |
Mouse | |
Protein G | |
RUO | |
Chemical | |
Antibody | |
IgG1 |
ELISA, Immunoprecipitation | |
8E11 | |
Unconjugated | |
Benzo[a]pyrenediol-epoxide; BPDE | |
BPDE. | |
100 μg | |
Primary | |
4°C | |
Liquid | |
Chemical |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction