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Invitrogen™ BPNT1 Polyclonal Antibody
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Catalog No. PIPA561743
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100 μL
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PIPA561743 100 μL
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Catalog No. PIPA561743 Supplier Invitrogen™ Supplier No. PA561743
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SEEVDQELIE DSQWEEILKQ PCPSQYSAIK EEDLVVWVDP LDGTKEYTEG LLDNVTVLIG IAYEGKAIAG VINQPYYNYE AGP Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BPNT1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Bpnt1
Gene Accession No. O95861
Gene Alias 3'(2'), 5'-bisphosphate nucleotidase 1; 3'(2'),5'-bisphosphate nucleotidase 1; Bisphosphate 3'-nucleotidase 1; BPNT1; BPntase; epididymis luminal protein 20; HEL20; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; Sal3; scHAL2 analogous 3; testicular tissue protein Li 29
Gene Symbols Bpnt1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human BPNT1. Recombinant protein control fragment (Product #RP-94410).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10380
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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