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BRD4 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501561488
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50 μL
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50-156-1488 50 μL
50-156-1487 100 μL
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Catalog No. 50-156-1488 Supplier Bethyl Laboratories, Inc Supplier No. A301985A50
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains.BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

Specifications

Antigen BRD4
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene BRD4
Gene Accession No. O60885, Q9ESU6
Gene Alias HUNK1
Gene Symbols Brd4
Host Species Rabbit
Immunogen Between 1312 and 1362
Purification Method Antigen affinity chromatography
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23476, 57261
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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