Brefeldin A, 98%

Description

CAS: 20350-15-6 | C16H24O4 | 280.36 g/mol

Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.

Solubility
Soluble in dimethylsulfoxide, dichloromethane and ethanol. Slightly soluble in water.

Notes
Store in cool place. Incompatible with strong oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 20350-15-6
• Molecular Formula: C16H24O4
• Molecular Weight (g/mol): 280.36
• MDL Number: MFCD00083258,MFCD12913297
• InChI Key: KQNZDYYTLMIZCT-PNFJWZTBSA-N
• Synonym: brefeldin a, cyanein, decumbin, bfa
• PubChem CID: 133640201
• SMILES: C[C@H]1CCC\C=C\[C@@H]2C[C@H](O)C[C@H]2[C@@H](O)\C=C\C(=O)O1

• Melting Point: 201°C to 205°C
• Color: White
• Quantity: 50 mg
• UN Number: UN2811
• Beilstein: 25191
• Merck Index: 14,1369
• Solubility Information: Soluble in dimethylsulfoxide,dichloromethane and ethanol. Slightly soluble in water.
• IUPAC Name: (1S,6S,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
• Formula Weight: 280.36
• Percent Purity: 99%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Brefeldin A

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
RTECSNumber	GY8410000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only