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Tocris Bioscience™ BS 181 dihydrochloride

Selective cdk7 inhibitor

$193.00 - $799.00

Specifications

Chemical Name or Material N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
Molecular Formula C22H32N6.2HCl
Product Type Target: Cyclin-dependent Kinase Inhibitors
Formula Weight 453.45
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
560810 View Documents Tocris Bioscience™
5608/10
10mg Each for $193.00
N/A
560850 View Documents Tocris Bioscience™
5608/50
50mg Each for $799.00
N/A
Description

Description

Selective cdk7 inhibitor (IC50 = 21 nM). Displays >40-fold selectivity for cdk7 over others cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice.
Specifications

Specifications

N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
C22H32N6.2HCl
Target: Cyclin-dependent Kinase Inhibitors
453.45
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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