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Lonza Walkersville PyroGene Bulk Recombinant Factor C Endpoint Fluorescent Assay
Supplier: Lonza Walkersville 50658NV
The PyroGene Recombinant Factor C Assay is the evolution of endotoxin detection testing. Lonza scientists have developed a recombinant form of Factor C, the first component in the horseshoe crab clotting cascade activated by endotoxin.Recombinant Factor C(rFC) is activated by endotoxin binding, and the active enzyme then cleaves a synthetic substrate, resulting in the generation of a fluorogenic compound.PyroGene rFC works through a single enzymatic step compared to the multiple step enzymatic process necessary for LAL assays.Benefits:Sensitivity range from 0.005 to 5 EU/mlHigher endotoxin specificity through the elimination of false positive glucan reactionsLess lot-to-lot variabilitySecurity of supplyFDA acknowledged alternative to LALApplications:In-process testingFinal product release testingWater testingTesting plant-based materialContent:30 x 96 tests/vialrFC enzyme solution30 x 6 mL/vial fluorogenic substrate30 x 5 mL/vial rFC assay buffer10 vials endotoxin
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