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Abcam Bufalin, Na+/K+-ATPase Inhibitor, Solid, >98% Purity, 50 mg

Catalog No. 502705090
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50-270-5090 50 mg
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Catalog No. 50-270-5090 Supplier Abcam Supplier No. AB14563650MG
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Description

Potent Na+/K+-ATPase inhibitor that induces cell differentiation and apoptosis.

  • Molecular Weight: 386.5 Da
  • Purity: >98%
  • Form: Solid
  • Mechanism of Action: Na+/K+-ATPase inhibitor; potent inhibitor of steroid receptor coactivators SRC-3 and SRC-1
  • Biological Activity: Induces cell differentiation and apoptosis; activates AP-1 via JNK; shows antitumor effects in vivo
  • Composition: 100% 3β-14-Dihydroxy-5β-bufa-20,22-dienolide

The product is subject to the following: Abcam Restricted Use Statement

Specifications

Content And Storage Store at -20°C.
Form Solid
Shipping Condition Ambient
Substrate Properties Chemical Substrate
Buffer 100% 3β-14-dihydroxy-5β-bufa-20,22-dienolide
Target Molecule Na+/K+-ATPase, SRC-3, SRC-1
Formulation 100% 3β-14-Dihydroxy-5β-bufa-20,22-dienolide
Quantity 50 mg
For Use With (Application) Na+/K+-ATPase inhibition, SRC-3 and SRC-1 inhibition, Induction of cell differentiation and apoptosis, AP-1 activation
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